
吕运开(Lv Yun-Kai),男,教授,硕士/博士研究生导师,生于1967年11月,河北省隆尧县人。1987年6月毕业于河北大学化学系,1999年获河北大学分析化学硕士学位,2004年获南开大学分析化学博士学位, 2005年在河北大学化学博士后流动站工作。1987年7月至今在河北大学化学与材料科学学院任教。联系方式:E-mail:lvyunkai@hbu.edu.cn
(一)主讲课程:分析化学进展、高等仪器分析、先进功能材料、化学与社会发展、食品营养与健康
(二)专业与研究方向:分析化学;荧光传感成像分析、中药有效成分的药理作用机制研究、微萃取分离分析
(三)研究领域与兴趣
1. 先进功能材料合成
[1] 多孔有机聚合物(POPs)合成及应用:金属有机骨架(MOFs)、共价有机骨架(COFs)、氢键有机框架材料(HOF)、共轭微孔聚合物(CMPs)、超交联聚合物(HCPs)、多孔配位聚合物(PCPs)。开发POPs新特性,包括纳米酶、绿色催化剂、高选择性吸附材料,分别应用于疾病标志物检测、光催化降解持久性有机污染物,分离富集食品中农兽药残留。
[2] 诊疗一体化荧光量子点的合成及应用
[3] 植物活性成分的分离甄定、药理作用机制研究及其复方制剂开发
[4] 高稳定性绿色催化剂合成及其应用
2. 仪器分析
(1)色谱-质谱联用技术:分析对象主要包括环境污染物、疾病标志物、农兽药残留、中草药活性成分等。
(2)荧光分析及成像分析:主要检测疾病标志物,以及研究植物活性成分与酶、蛋白质、外泌体、癌细胞、肿瘤标志物等的作用机制。
[15] 晨光生物科技集团股份有限公司(横20250185):多糖类样品的检测,2025.9.26-2026.9.26
[14] 河北宝顺新型建材科技有限公司(横20250178):高效菱镁胶凝材料改性剂的开发,2025.10.01-2026.10.31
[13] 2022年河北省重大科技成果转化专项(22281403Z): 苯部分加氢及环己烯水合催化剂开发及应用,2022.7-2024.12,合作单位:开滦能源化工股份有限公司,燕山大学,河北大学
[12] 开滦能源化工股份有限公司(合同编号:横20220057):聚萘二甲酸乙二醇酯合成中间产品检测技术开发,2022.5-2023.5技术合同认定登记号:2022130601000260,合同类别:技术开发
[11] 河北省教育厅(QN2021016): 山楂原花青素的抗衰老活性及构效关系研究, 2021.1-2023.12
[10] 2019年度河北大学自然科学多学科交叉研究计划项目(DXK201906):基于功能化硫量子点的肿瘤标志物检测技术研究,2019.1-2019.12
[9] 河北省自然科学基金资助项目(B2016201213):金属有机骨架复合材料的合成及其在室内有害气体富集检测中应用,2016.1-2018.12
[8] 开滦集团项目(合同编号:KL煤化工[2016]282号):复合材料分析检测技术开发及其阻燃剂研究中的应用,2016.5-2017.5
[7] 国家自然科学基金资助项目(21375032):基于限进介质-分子印迹磁性微球的食品中抗生素残留选择性萃取净化体系研究,2014.1-2017.12。
[6] 河北省自然科学基金资助项目(B2011201081):分子印迹杂化材料制备及在线SPE-HPLC分离分析新方法研究,2011.1-2013.12。
[5] 河北省应用基础研究计划重点基础研究项目(10967126D):乳制品及相关食品的样品处理新技术与有毒有害物质关键检测技术研究,2010.1-2012.12。
[4] 国家自然科学基金资助项目(20675024):新型分子印迹材料制备方法的研究及其在食品安全检测中的应用,2007.1-2009.12。
[3] 河北省教育厅科学计划项目(2006407):基于动物源食品安全分析的新型色谱分离介质研究,2007.1-2009.12。
[2] 第三十七批中国博士后科学基金(2005037629):溶胶-凝胶色谱固定相的制备及兽药残留分析新方法研究,2005.1-2005.12。
[1] 河北大学自然科学研究计划项目:食品中痕量有毒元素及有机污染物分离富集新技术方法研究,2005.1-2008.12。
2025年高等教育(研究生)河北省教学成果奖一等奖:价值引领-交叉融合-创新驱动”三位一体的研究生人才培养模式探索与实践
2023年度获河北省科技进步奖二等奖:食品中农兽药残留快速灵敏高通量检测关键技术开发及应用
2020年度获河北省高校党建研究课题(GXDJ2020B005)三等奖
2016年度获河北省科学技术进步二等奖:生物分子高灵敏度质谱检测新技术研究
2014年度获河北省自然科学三等奖:基于多孔功能分离材料的微型化复杂样品萃取分离技术。
2007年度获天津市自然科学一等奖:金属组学和环境化学中的分析新技术和新方法研究。
2003年获中国分析测试协会科学技术一等奖
1998年被评为河北大学优秀党员
1997年被河北大学授予一九九六年度科研重要贡献奖
1992年度获河北大学优秀学生工作者
[20] 发明专利(CN202311641067.9):氯功能化共价有机框架/石墨烯气凝胶材料、其制备方法及应用. 公开日:20251104.
[19] 发明专利(CN202510675356.3):多功能生物基超交联聚合物及其制备方法与应用. 公开日:20250919.
[18] 发明专利(CN202510284895.4):硫酸卡那霉素识别荧光传感器及硫酸卡那霉素检测方法. 公开日:2025.05.30.
[17] 发明专利(CN202411841484.2):采用双功能硫纳米点对食品中诱惑红进行检测的方法. 公开日:2025.03.21.
[16 发明专利(CN202410922316.X):一种环己烯水合制备环己醇的方法. 公开日:20241105.
[15] 发明专利(CN202410477129.5):用于环己烯水合制环己醇的催化剂、其合成方法及应用. 公开日:20240809.
[14] 发明专利(CN202448410355855.X):一种氧化石墨烯/超亲水分子印迹树脂材料、其制备方法及应用. 公开日:20240709.
[13] 发明专利(CN202311756877.9):一种多孔聚合物微球固相微萃取纤维及其制备方法与应用. 公开日:2024.02.13.
[12] 发明专利(CN202210784402.X):一种分子印迹固相微萃取纤维涂层及其制备方法与应用,授权公告日:2023.07.04
[11] 发明专利(CN202110537807.9):一种离子液体-多级孔道酚醛树脂及其制备方法与应用,授权公告日:2022.07.12
[10] 发明专利(201910949536.0):一种硫量子点/二氧化锰纳米片复合材料及其制备方法与应用,授权公告日:2022.06.03.
[9] 实用新型专利(CN202020578910.9):一种金属有机骨架固相微萃取装置,授权公告日:2021.04.13.
[8] 实用新型专利(CN201922218501.8):一种化学分析用溶剂萃取装置,授权公告日:2020.10.09.
[7] 发明专利(201910116267.X):一种固相微萃取纤维及其制备方法,公开日:2019.05.21
[6] 发明专利(201711062548.9):一种阻燃抗静电聚甲醛复合材料及其制备方法,公开日期:2018.05.25
[5] 发明专利(201810075690.5):一种高强高灼热丝阻燃聚丙烯及其制备方法, 公开日期:2018.07.24.
[4] 发明专利:CN201410195035.5,一种外表面亲水性杂化复合固相萃取吸附剂的制备方法. 公告日:2015.12.30.
[3] 发明专利:CN201410195033.6,一种外表面亲水的分子印迹磁性硅胶微球的制备方法. 公告日:2015.12.02.
[5] 发明专利(201810075690.5):一种高强高灼热丝阻燃聚丙烯及其制备方法, 公开日期:2018.07.24.
[4] 发明专利:CN201410195035.5,一种外表面亲水性杂化复合固相萃取吸附剂的制备方法.公告日:2015.12.30.
[3] 发明专利:CN201410195033.6,一种外表面亲水的分子印迹磁性硅胶微球的制备方法.公告日:2015.12.02.
[2] 发明专利:CN201410195140.9,一种外表面亲水性大孔有机-无机杂化整体柱的制备方法. 公告日:2015.10.28.
[1] 发明专利(CN201410140078.3):一种恩诺沙星分子印迹整体柱的制备方法,公告日:2015.04.08.
[150] Duan Lian-Lian, Liu Wen-Jun, Zhai Rui, Wang Zhen-Guang, Yan Hong-Yuan, Lv Yun-Kai*. Construction of BSA-CuNCs@UiO-66 Nanoprobe Based on MOF Confinement Effect and Its Ultrasensitive Fluorescence Sensing for Creatinine. Spectrochim. Acta A, 2026, 351: 127515. DOI: 10.1016/j.saa.2026.127515
[149] Chen, Dongbo; Niu, Minhui ; Li, Xintong; Sun, Shaohan; Lv, Yun-Kai*; Wang, Henggang; Wang, Zhenguang. Automatic Image Processing-Assisted Ratiometric Afterglow Sensor Array for the Discrimination and Detection of Fluoroquinolones Enabled by a Universal Host-Guest Strategy. Analytical Chemistry, 2025, 97(29):15969-15979. DOI:10.1021/acs.analchem.5c02680
[148] Wang Nian-Min , Shi Lei*, Liu Yan-Bing , Zhang Xiao-Long , Yu Li-Qing , Shen Shi-Gang , Lv Yun-Kai*. Interaction Mechanism between Andrographolide and α-Glucosidase: Multispectroscopy and Molecular Docking Analyses. Luminescence, 2025, 40(6): e70206. DOI:10.1002/bio.70206
[147] Yi Chen, Heman Qin, Qian Zhang, Yatao Wang, Yunkai Lv, Libo Niu. Sulfonic acid group modified ZSM-5 zeolite as a highly active catalyst for the hydration of cyclohexene to cyclohexanol. Journal of Chemical Sciences, 2025, 137: 34. DOI:10.1007/s12039-025-02350-5
[146] 刘秋玲,陈毅,张倩,刘树俊,吕运开,牛立博.镍基纳米催化剂催化糠醛转移加氢制备糠醇.精细化工, 2025, 42(5):1063-1072. DOI:10.13550/j.jxhg.20240429
[145] 牛立博, 薛宇恋, 张倩, 王亚涛, 徐肇中, 陈毅, 吕运开*. 全氟磺酸树脂改性ZSM-5催化剂用于环己烯水合研究,河北大学学报,2025, 45(1): 60-69. DOI:10.3969/j.issn.10001565.2025.01.007
[144] Lin, Shumin; Lv, Yun-Kai; Zhu, Aixue; Su, Ming; Li, Xiliang; Liang, Shu-Xuan. Development of a NiFe2O4 covalent organic framework based magnetic solid-phase extraction approach for specific capture of quinolones in animal innards prior to UHPLC–Q–Orbitrap HRMS detection. Food Chemistry, 2024, 454: 139796. DOI:10.1016/j.foodchem.2024.139796
[143] Shi, Xiao-Ye; Liu, Shu-Jun; Yu, Li-Qing; Li, Lan-Fen; Lv, Yun-Kai, MOFs with 2,6-naphthalene dicarboxylic acid as organic ligand for solid phase microextraction of aldehyde biomarkers in the exhalation of lung cancer patients, Talanta Open, 2024, 9: 100286. DOI: 10.1016/j.talo.2023.100286
[142] Yang, Xiao-Qin; Yu, Li -Qing; Li, Lan-Fen; Lv, Yun-Kai, Enhancing the water-resistance of MOF-199 film through incorporation of microporous organic networks for solid-phase microextraction of BTEX in aqueous environments with improved efficiency, Analytica Chimica Acta, 2024, 1294: 342293. DOI: 10.1016/j.aca.2024.342293
[141] 李攀,彭珊,孙月娜,李晗,李佳怡,张淼,贾光,吕运开*. 构建实验室安全教育体系提高应急处置能力, 实验室科学, 2024, 27(3): 189-193. DOI:10.3969/j.issn.1672-4305.2024.03.041
[140] Hao Qi-Long, Wang Shuo-Wen, Yu Li-Qing, Yang Xiao-Qin, Lv Yun-Kai. Immobilization of zeolitic imidazolate framework-90 onto modified stainless steel wire via covalent bonding for solid-phase microextraction of biomarkers in exhalation of lung cancer patients. Separation Science Plus, 2023, 6(7): 2300026. DOI:10.1002/sscp.202300026
[139] Hao, Qi-Long; Yu, Li-Qing; Yang, Xiao-Qin; Xu, Rui-Ting; Lv, Yun-Kai. Two-Dimensional Nitrogen-Doped Carbon Nanosheets Derived from g-C3N4/ZIF-8 for Solid-Phase Microextraction in Exhalation of Esophageal Cancer Patients. ACS Applied Materials & Interfaces, 2023, 15(4): 5990–5997. DOI:10.1021/acsami.2c21858
[138] Sun Yue-Na, Shi Lei, Shi Mei-Li, Yu Li-Qing, Yan Hong-Yuan, Lv Yun-Kai. Chiral organic-silica hybrid monolithic HPLC column with dynamic grafting BSA for the enantiomeric separation. Microchemical Journal, 2023, 193: 109093. DOI:10.1016/j.microc.2023.109093.
[137] 孙月娜, 李攀, 赵文革, 赵金灿, 闰明涛, 吕运开. 基于科研创新能力培养的化学实验设计与实践. 实验室科学, 2023, 26(3): 56-58+63. DOI:10.3969/j.issn.1672-4305.2023.03.015.
[136] 孙月娜,王欢,李 攀,闰明涛,李 晗,吕运开,BiOClxI1-x@NH2-MIL-125(Ti)的制备及其光催化性能综合实验,实验技术与管理, 2023,40(5): 57-62. DOI:10.16791/j.cnki.sjg.2023.05.009.
[135] Hu Si-Yu, Sun Yue-Na, Feng Zhi-Wen, Wang Fei-Ou, Lv Yun-kai* Design and construction strategies to improve covalent organic frameworks photocatalyst's performance for degradation of organic pollutants. Chemosphere, 2022, 286: 131646. DOI:10.1016/j.chemosphere.2021.131646.
[134] Jiang Xiao-Xue, Li Pan*, Zhao Meng-Ya, Chen Rui-Cong, Wang Zhen-Guang, Xie Jia-Xiu, Lv Yun-Kai*. In situ encapsulation of SQDs by zinc ion-induced ZIF-8 growth strategy for fluorescent and colorimetric dual-signal detection of alkaline phosphatase, Analytica Chimica Acta, 2022, 1221: 340103. DOI:10.1016/j.aca.2022.340103.
[133] Jiang Xiao-Xue, Sun Yue-Na*, Zhang Chen, Yang Zhao, Yu Li-Qing, Lv* Yun-Kai. Synthesis of SiO2@MOF-199 as a fiber coating for headspace solid-phase microextraction of phthalates in plastic bottled milk. Chromatographia, 2022, 85: 851-863. DOI:10.1007/s10337-022-04184-6
[132] Li Yuan1, Jiang Xiao-Xue1, Xie Jia-Xiu, Lv Yun-kai*. Recent advances in the application and mechanism of carbon dots/metal-organic frameworks hybrids in photocatalysis and the detection of environmental pollutants. Chemistry-An Asian Journal, 2022, 17(13): e202200283. DOI:10.1002/asia.202200283
[131] Shi Lei, Lv Yun-Kai*, Wang Jiang-Wang, Yang Lan-Lan, Shen Shi-Gang*. A novel thiolysis-high-performance liquid chromatography method for the determination of proanthocyanidins in grape seeds. Journal of Separation Science, 2022, 45: 1874-1883. DOI:10.1002/jssc.202200003
[130] Yu Zhengming, Lv Yunkai*, Huang Feng, Zhang Fang, Shi Qi, An Ke, Fan Tingting, Li Gang, Wang Jing*. Photoatalytic degradation of organic pollutants in water under visible light by NH2-MIL-125(Ti-Zr)@BiOClxI1-x composite photocatalyst. ChemistrySelect, 2022, 7(28): e202201958. DOI:10.1002/slct.202201958
[129] Yu Zhengming, Lv Yunkai*, Zhang Fang, Shi Qi, An Ke, Huang Feng, Fan Tingting, Li Gang, Wang Jing*. Catalytic degradation of organic pollutants in water under visible light by BiOCl@NH2-MIL-125(Ti-Zr) composite photocatalyst. J Mater Sci: Mater Electron, 2022, 33(24): 19599-19611. DOI:10.1007/s10854-022-08797-3
[128] 孙月娜,李攀,赵文革,杜建龙,闰明涛,吕运开*. NH2-MIL-53(Fe)/GO的制备及其光催化性能分析综合化学实验设计. 实验室研究与探索, 2022, 41(10)164-168. DOI:10.19927/j.cnki.syyt.2022.10.000
[127] Jiang Xiao-Xue, Yu Li-Qing *, Sun Yue-Na, Li Yuan, Li Hui-Min, Lv Yun-Kai*. Hollow Zeolitic Imidazolate Framework-7 coated stainless steel fiber for solid phase microextraction of volatile biomarkers in headspace gas of breast cancer cell lines. Analytica Chimica Acta, 2021, 1181: 338901. DOI:10.1016/j.aca.2021.338901.
[126] Liang Linlin, Lv Yunkai*, Yu Zhengming, Wu Ruifang, Shi Qi, Chen Hua and Wang Jing*. Surface plasmon resonance effect of Ag@BiOCl and its enhanced visible light-photodegradation of acid red B. Journal of Materials Science: Materials in Electronics, 2021, 32(14): 18646-18656. DOI:10.1007/s10854-021-06352-0.
[125] Ma Meng-Yuan, Yu Li-Qing *, Wang Shuo-Wen, Meng Ying, and Lv Yun-Kai*. Hybrid ZIF-8-90 for selective solid-phase microextraction of exhaled breath from gastric cancer patients. ACS Applied Bio Materials, 2021, 4(4): 3608-3613. DOI:10.1021/acsabm.1c00107.
[124] Shi Lei, Wang Jang-Wang, Lv Yyun-Kai*. Research progress on analysis methods of procyanidins. IOP Con. Ser. Earth Environ. Sci., 2021, 705: 012006. http://doi.org/10.1088/1755-1315/705/1/012006.
[123] Liang, Linlin; Wang, Jing*; Wu, Ruifang; Li, Zekai; Yan, Xiaoran; Lv, Yunkai*. Preparation of BiOCl1-xIx solid solution and its visible light photocatalytic performance. Journal of Materials Science-Materials in Electronics,2020, 31(4): 2817-2825. DOI:10.1007/s10854-019-02825-5.
[122] Wang Chen-Feng+, Sun Xin-Yue+, Su Ming*, Wang Yi-Peng and Lv Yun-Kai*. Electrochemical biosensors based on antibodies, nucleic acids and enzymes functionalized graphene for the detection of disease-related biomolecules. Analyst, 2020, 145(5): 1550-1562. DOI:10.1039/C9AN02047K.
[121] Zhang Xi, Wang Jing*, Dong Xing-Xing, Lv Yun-Kai*. Functionalized metal-organic frameworks for photocatalytic degradation of organic pollutants in environment. Chemosphere, 2020, 242: 125144. DOI:10.1016/j.chemosphere.2019.125144.
[120] Huang, Li-Fei; Jia, Bo; Jiang, Lin; Liu, Wei-Lun; Xia, Li-Ya; Lv, Yun-Kai*. Preparation of restricted-access material precolumns by grafting δ-gluconolactone on hybrid silica monolithic column for on-line solid-phase extraction of tetracyclines residues from milk. Journal of Separation Science, 2019, 42: 843-850. DOI:10.1002/jssc.201801130.
[119] Jia Bo, Cui Meng-Jiao, Yang Ceng-Ceng, Hu Si-Yu, Lv Yun-Kai*. Adsorption characteristics of monodisperse magnetic cation exchange microspheres prepared based on swell-penetration method. Journal of Applied Polymer Science, 2019, 136, 48019. DOI:10.1002/APP.48019.
[118] Liang Linlin, Wang Jing*, Song Aizhen, Wu Ruifang, Chen Danyang and Lv Yunkai*. Doping effects of Nb on the dielectric properties of (Pb,La,Sr)(Zr,Sn,Ti,Nb)O3 X9R ceramic materials, Ferroelectrics, 2019, 550(1): 183-189, DOI:10.1080/00150193.2019.1652506.
[117] Ma Yao-Jia+, Jiang Xiao-Xue+, Lv Yun-Kai*. Research progress in the preparation and application of magnetic metal-organic framework composites. Chemistry-An Asian Journal, 2019, 14, 3515 – 3530. DOI:10.1002/asia.201901139.
[116] Yu Li-Qing*, Su Fei-Hong, Ma Meng-Yuan, Lv Yun-Kai*. Metal-organic frameworks for the sorption of acetone and isopropanol in exhaled breath of diabetics prior to quantitation by gas chromatography. Microchimica Acta, 2019, 186(8): 588. DOI:10.1007/s00604-019-3713-1.
[115] 孙月娜, 李攀, 赵文革, 吕运开*. 参与式教学模式在有机化学实验教学中的应用, 实验室科学, 2019, 22(3): 122-124+127. DOI:10.3969/j.issn.1672-4305.2019.03.032.
[114] 赵娜, 梁嘉诚, 时丽艳, 吕运开, 于丽青*. QuEChERS-高效液相色谱-串联质谱法同时测定有机肥料中10种氟喹诺酮类药物残留, 色谱,2019, 37(3): 313-318. DOI:10.3724/SP.J.1123.2018.11002.
[113] 赵娜, 孙月娜, 时丽艳, 李攀, 吕运开*. 化妆品塑料包装中16种增塑剂的迁移规律. 河北大学学报(自然科学版), 2019, 39(3): 270-277. DOI:10.3969/j.issn.1000-1565.2019.03.008.
[112] Liu Chang, Yu Li-Qing, Zhao Ya-Ting, Lv Yun-Kai*. Recent advances in metal-organic frameworks for adsorption of common aromatic pollutants. Microchim Acta, 2018, 185(7): 342. DOI:10.1007/s00604-018-2879-2.
[111] Wang Chen-Feng, Wang Zhen-Guang, Sun Xin-Yue, Chen Meng-Jiao and Lv Yun-Kai*. An ultrasensitive fluorescent aptasensor for detection of cancer marker protein based on graphene oxide-ssDNA, RSC Advances, 2018, 8, 41143-41149. DOI:10.1039/c8ra08078j.
[110] Wang Si-Ying, Wang Chen-Feng, Lv Yun-Kai*, Shen Shi-Gang. Fabrication of fluorescent biosensing platform based on graphene oxide-DNA and their application in biomolecule detection. Trends in Analytical Chemistry, 2018, 106: 53-61. DOI:10.1016/j.trac.2018.07.004.
[109] Yu Li-Qing*, Wang Li-Ya, Su Fei-Hong, Hao Ping-Yu, Wang Huan, Lv Yun-Kai*. A gate-opening controlled metal-organic framework for selective solid-phase microextraction of aldehydes from exhaled breath of lung cancer patients. Microchim Acta, 2018, 185(6): 307. DOI:10.1007/s00604-018-2843-1.
[108] Zhang Qi, Wang Chen-Feng, Lv Yun-Kai*. Luminescent switch sensors for the detection of biomolecules based on metal-organic frameworks. Analyst, 2018, 143, 4221-4229. DOI:10.1039/C8AN00816G.
[107] Zhao Ya-Ting, Yu Li-Qing, Xia Xin, Yang Xin-Yu, Hu Wei, Lv Yun-Kai*. Evaluation of adsorption and desorption properties of zeolitic imidazolate framework-7 for volatile organic compounds through thermal desorption-gas chromatography. Analytical Methods, 2018, 10(40) 4894-4901. DOI:10.1039/C8AY01856A.
[106] 董焕新, 吕二盼, 詹磊, 吕运开*. 食品中动物源性成分的多重PCR快速检测. 食品安全质量检测学报, 2018, 9(17): 4595-4600. DOI: CNKI: SUN:SPAJ.0.2018-17-025.
[105] 马俊琴, 于小慧, 贾翠玲, 吕运开*. 分子印迹杂化介孔硅胶材料的制备及固相萃取-高效液相色谱法测定鳕鱼中氟喹诺酮类兽药残留. 食品安全质量检测学报, 2018, 9(3): 540-546. DOI:10.3969/j.issn.2095-0381.2018.03.014.
[104] 马瑶佳, 张茜, 贾博, 吕运开*. 功能化磁性纳米粒子在污水处理中的应用进展. 中国给水排水, 2018, 34(22): 31-36. DOI: CNKI: SUN: GSPS.0.2018-22-011.
[103] 张琪,马瑶佳,艾连峰,吕运开*. 基于轻质萃取剂的涡旋辅助分散液液微萃取-气相色谱法测定瓶装水中塑化剂. 河北大学学报, 2018, 38 (1): 33-40. DOI:10.3969/j.issn.1000 1565.2018.01.006.
[102] 张茜, 刘炜伦, 路亚楠,吕运开*. 顶空气相色谱-质谱联用技术的应用进展. 色谱, 2018, 36(10): 962-971. DOI:10.3724/ SP.J.1123.2018.05013.
[101] 周少丹,唐嘉琦,贾博,吕运开*. 表面接枝亲水性聚合物刷磁性微球的制备及其对蜂蜜中四环素类抗生素残留的磁分散固相萃取, 色谱, 2018, 38(2): 85-93. DOI:10.3724/SP.J.1123.2017.10026.
[100] Cao Guo-Chuang, Wang Si-Ying, Lv Yun-Kai*. The controllable synthesis of the hybrid silica monolithic materials with the stable skeleton macroporous structure. Advances in Engineering Research, 2017, 82: 223-226.
[99] Lv Yun-Kai*, Xiong Xue, Zhao Fang-Fang, Li Meng-Zhe, Wang Mian and Li Xiao-Yang. Preparation of magnetic surface-imprinted polymer microspheres with hydrophilic external layers for selective extraction of fluoroquinolones from eggs. Australian Journal of Chemistry, 2017, 70(3): 237-244. DOI: 10.1071/CH16250.
[98] 蔡少凡, 金秋, 魏海英, 吕运开*. 表面连接与核-壳型键合FITC荧光纳米硅球的制备及性能比较. 河北大学学报, 2017, 37(3): 248-253+261. DOI: 10.3969/j.issn.1000-1565.2017.03.005.
[97] 刘畅, 张奇, 王思颖, 董焕新, 吕运开*. 驴肉及其制品真伪鉴别技术研究进展. 食品安全质量检测学报, 2017, 8(7): 2657-2663. DOI:10.3969/j.issn.2095-0381.2017.07.043.
[96] 张奇, 刘畅, 王思颖, 吕运开*. 基于分子印迹整体柱的在线固相萃取-液相色谱联用测定奶粉中四环素类兽药残留. 食品安全质量检测学报, 2017, 8(7): 2692-2697. DOI:10.3969/j.issn.2095-0381.2017.07.048.
[95] Lv Yun-Kai*, Zhang Jing, Li Meng-Zhe, Zhou Shao-Dan, Ren Xing-Hui and Wang Jing. Fast clean-up and selective enrichment of florfenicol in milk by restricted access media molecularly imprinted magnetic microspheres based on surface-initiated photoiniferter-mediated polymerization. Analytical Methods, 2016, 8(19): 3982-3989.
[94] 郭萌萌, 刘雪卉, 吕运开, 马俊琴. 磁分散萃取-液相色谱法测定食品接触材料中3种酚类物质迁移量. 食品安全质量检测学报, 2016, 7(1): 285-290. CNKI: SUN:SPAJ.0.2016-01-054.
[93] 张静, 吕运开, 于丽青. 磁性微球表面光引发聚合制备金属配位印迹层及选择性富集奶样中氟喹诺酮类药物残留. 食品安全质量检测学报, 2016, 7(1): 276-284. CNKI:SUN:SPAJ.0.2016-01-053.
[92] 张秋菊, 刘保生, 李改霞, 韩荣, 吕运开. 共振光散射法研究硫酸粘杆菌素与牛血清白蛋白间的反应机理. 光谱学与光谱分析, 2016, 36(9): 2879-2883. DOI: 10.3964/j.issn.1000-0593(2016)09-2879-05.
[91] Lv Yun-Kai*, Guo Zhi-Yong, Wang Jin-Zhi, Guo Meng-Meng, Yu Lin-Kang, Fang Hui. Preparation of a restricted access material–macroporous hybrid monolithic column for on-line solid-phase extraction of the sulfonamides residues from honey. Analytical Methods, 2015, 7(4), 1563-1571. DOI:10.1039/c4ay02787f.
[90] Lv Yun-Kai*, He Yan-Dong, Xiong Xue, Wang Jin-Zhi, Wang Hai-Yan, Han Ya-Meng. Layer-by-layer fabrication of restricted access media-molecularly imprinted magnetic microspheres for magnetic dispersion microextraction of bisphenol A from milk samples. New Journal of Chemistry, 2015, 39(3), 1792-1799. DOI:10.1039/c4nj01882f.
[89] Lv Yun-Kai*, Zhang Jing-Qi, Guo Zhi-Yong, Zhang Wei, Sun Han-Wen. Determination of tetracyclines residues in egg, milk, and milk powder by on-line coupling of a precolumn packed with molecular imprinted hybrid composite materials to RP-HPLC-UV. Journal of Liquid Chromatography & Related Technologies, 2015, 38 (1): 1-7. DOI:10.1080/10826076.2013.873873.
[88] Lv Yun-Kai*, Zhang Wei, Guo Meng-Meng, Zhao Fang-Fang, Du Xiao-Xue. Centrifugal microextraction tube-cloud point extraction coupled with gas chromatography for simultaneous determination of six phthalate esters in mineral water. Analytical Methods, 2015, 7(2): 560-565. DOI:10.1039/c4ay01705f.
[87] 孙汉文, 孟哲, 石志红, 吕运开. UPLC-Q-TOF/MS法鉴定兽药磺胺二甲嘧啶在小鼠血液和尿液中的代谢产物. 河北大学学报(自然科学版), 2015, 35(2): 131-137+224. DOI: 10.3969/j.issn.1000-1565.2015.02.005
[86] Li Na, Lv Shu-Fang, Lv Yun-Kai*, Xiong Xue, Li Bao-Hui. Magnetic Dispersion Extraction of Tetracyclines Residues from Milk by Chlortetracycline-Imprinted Magnetic Composite Microspheres. Asian J. Chem., 2014, 26(12), 3535-3540. DOI: 10.14233/ajchem.2014.16195.
[85] Lv Yun-Ka*, Zhang Jing-Qi, Zhang Wei, Wang Wen-Cai, Li Bao-Hui. Molecularly Imprinted Solid-Phase Extraction of Tetracyclines Residue from Milk Using Internal-Surface Reversed-Phase Hybrid Composite Packing Materials. Asian J. Chem., 2014, 26(12), 3541-3544. DOI: 10.14233/ajchem.2014.16198.
[84] Lv Yun-Kai*, Li Pan, Jiao Miao-Lun, Liu Bao-Sheng, Yang Chao. Fluorescence quenching study of moxifloxacin interaction with calf thymus DNA. Turkish Journal of Chemistry, 2014, 38(2): 202-209. DOI:10.3906/kim-1301-28.
[83] Lv Yun-Kai,* Zhang Jing-Qi, He Yan-Dong, Zhang Jing, Sun Han-Wen. Adsorption-controlled preparation of molecularly imprinted hybrid composites for selective extraction of tetracyclines residues from honey and milk. New Journal of Chemistry, 2014, 38 (2): 802–808. DOI:10.1039/c3nj00962a.
[82] Sun Yue-Na, Qin Xin-Ying, Lv Yun-Kai*, Li Shan-Ze, Wei Chen. Simultaneous Determination of Five Phytohormones in Mungbean Sprouts of China by Micellar Electrokinetic Chromatography. Journal of Chromatographic Science, 2014, 52 (7), 725-729. DOI:10.1093/chromsci/bmt102.
[81] 郭莹, 刘保生, 李志云, 张丽惠, 吕运开. 不同方程计算药物小分子与蛋白结合常数的比较研究. 发光学报, 2014, 35(9): 1114-1119. DOI: 10. 3788 /fgxb20143509. 1114.
[80] 孟哲, 石志红, 吕运开, 孙汉文. 超高效液相色谱-高分辨四级杆飞行时间质谱法快速筛查乳制品中磺胺类与氟喹诺酮类药物. 分析化学 2014, 42(10): 1493-1500. DOI: 10. 11895 /j. issn. 0253-3820. 140299.
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[78] Li Xiao-Liu, Liu Zheng-Hao*, Lv Yun-Kai, Gao Jun-Gang, Zhai Xue-Fei, Huang Ya-Jing. Optimization of Molecularly Imprinted Poly (MAA-co-AM) Composite Membranes for Evaluation of Chlorimuron-Ethyl Herbicide. Asian Journal of Chemistry, 2013, 25(6), 3473-3478. DOI: 10.14233/ajchem.2013.14083.
[77] Lv Yun-Kai *, Liu Xiao-Hui, Yan Shuai-Lei, Zhang Yan, Sun Han-Wen, Synthesis and characterization of the molecularly imprinted mesoporous silica based on the self-assembly technique for selective recognition of lomefloxacin in aqueous solution. Journal of Porous Materials, 2013, 20(5): 1345-1352. DOI:10.1007/s10934-013-9720-4.
[76] Lv Yun-Kai *, Zhao Chen-Xi, Li Pan, He Yan-Dong, Yang Zhong-Rui, Sun Han-Wen. Preparation of doxycycline-imprinted magnetic microspheres by inverse-emulsion suspension polymerization for magnetic dispersion extraction of tetracyclines from milk samples. Journal of Separation Science, 2013, 36(16): 2656-2663. DOI:10.1002/jssc.201300429.
[75] Lv Yun-Kai*, Jia Cui-Ling, Zhang Jing-Qi, Li Pan, Sun Han-Wen. Preparation and Characterization of Molecularly Imprinted Monolithic Column for On-Line Solid-Phase Extraction Coupled with HPLC for Determination of the Fluoroquinolone Residues in Honey Samples. Journal of Liquid Chromatography & Related Technologies, 2013, 36(2): 249-260. DOI:10.1080/10826076.2011.649877.
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[73] Zhang Dong, Lv Yun-Kai*, Chen Rong, Shi Chen-Chen. Preparation and Evaluation of a Molecularly Imprinted Sol-Gel Hybrid Material for Selective Solid-Phase Extraction of Sarafloxacin in Milk. Asian Journal of Chemistry, 2013, 25(7), 3922-3926.
[72] 吕运开*, 张静琦, 王晓虎, 李攀, 刘晓辉. 基于分子印迹聚合物微球的在线固相萃取-液相色谱联用技术测定牛奶中酰胺醇类药物残留. 食品科学, 2013, 34(16): 238-242. DOI:10.7506/spkx1002-6630-201316048.
[71] Liu, Bao-Sheng; Xue, Chun-Li; Wang, Jing; Yang, Chao; Lv, Yun-Kai. Study of the conjugation reaction between bovine serum albumin and gentamicin with Ponceau S as fluorescence probe. Monatshefte Fur Chemie, 2012, 143(2): 203-209. DOI, 10.1007/s00706-011-0585-4.
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[69] Liu, Baosheng; Yang, Chao; Yan, Xiaona; Wang, Jing; Lv, Yunkai. Study on the conjugation mechanism of colistin sulfate with bovine serum albumin and effect of the metal ions on the reaction. Journal of Luminescence, 2012, 132(5): 1133-1138. DOI, 10.1016/j.jlumin.2011.12.082.
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[66] Lv Yun-Kai*, Ma Yong, Zhao Xiao-Bo, Jia Cui-Ling, Sun Han-Wen. Grafting of norfloxacin imprinted polymeric membranes on silica surface for the selective solid-phase extraction of fluoroquinolones in fish samples. Talanta, 2012, 89, 270-275. DOI: 10.1016/j.talanta.2011.12.026.
[65] Lv Yun-Kai*, Wang Li-Min, Yan Shuai-Lei, Wang Xiao-Hu, Wang Zhen-Guang. Synthesis and Characterization of Molecularly Imprinted PMAA/SiO2 Hybrid Composite Materials for Selective Recognition of Lincomycin in Aqueous Media. Journal of Applied Polymer Science, 2012, 126, 1631-1636. DOI: 10.1002/app.36795.
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[62] Lv Yun-Kai*, Wang Xiao-Hu, Zhang Wei, Yang Lei, Liu Ping. Preparation of molecularly imprinted microspheres for solid-phase extraction coupled with HPLC for determination of the florfenicol residue in milk. International Journal of Science Innovations and Discoveries, 2012, 2(6), 610-616.
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[53] Lv Yun-Kai*, Sun Yue-Na, Wang Li-Min, Jia Cui-Ling, Sun Han-Wen. A simple and high-throughput method of ultrasonic extraction-capillary electrophoresis for determination of melamine in milk. Analytical Methods, 2011, 3(11), 2557-2561. DOI: 10.1039/c1ay05426k
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[51] Lv Yun-Kai*, Zhao Mi-Ge, Zhang Dong, Yan Hong-Yuan. Enrofloxacin-imprinted monolithic HPLC columns synthesized by in situ copolymerization for chromatographic separation. Journal of Liquid Chromatography & Related Technologies, 2011, 34(9), 705-718. DOI: 10.1080/10826076.2011.562592.
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[49] 刘宝圣, 吕运开*, 郭春海, 陈瑞春. 气相色谱法检测干辣椒中的11种农药残留量. 化学分析计量, 2011, 20(3), 50-52.
[48] 吕运开*, 孙月娜, 王晓虎, 赵晨曦. 分子印迹固相萃取-毛细管电泳法同时测定水中酚类物质. 中国给水排水, 2011, 27(24), 96-98.
[47] 秦丽娟,吕运开*. 离子对反相高效液相色谱法直接测定鸡肉组织中六种氟喹诺酮类药物残留. 广东化工, 2011, 38(5), 309-311.
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[44] 孙汉文, 李挥, 康占省, 张敬轩, 吕运开. 气相色谱-质谱法同时检测婴幼儿配方奶粉中的6种雌激素残留. 河北大学学报, 2011, 31(6): 607-611.
[43] 夏良艳, 孙建民, 吕运开, 孙汉文. 不同品牌纯牛奶中12种元素的比例分布. 微量元素与健康研究, 2011, 28(4): 33-34.
[42] 刘保生, 王晶, 薛春丽, 杨超, 吕运开. 头孢噻肟钠和氯霉素与牛血清白蛋白相互作用的荧光光谱分析. 发光学报, 2011, 32(6): 628-635.
[41] 刘保生, 闫潇娜, 杨超, 张彦青,吕运开. 诺氟沙星与氧氟沙星同时与牛血清白蛋白分子作用的荧光光谱. 河北大学学报, 2011, 31(3): 262-266.
[40] 刘保生, 杨超, 王晶, 薛春丽, 吕运开. 硫酸头孢匹罗与牛血清白蛋白结合反应的发光机理. 发光学报, 2011, 32(3): 293-299.
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[37] 刘保生, 薛春丽, 王晶, 杨超, 吕运开. 环丙沙星、氧氟沙星同时与牛血清白蛋白分子作用的荧光光谱. 发光学报, 2010, 31(2): 285-290.
[36] 霍利, 吕运开*, 丁天慧. 高效毛细管电泳浊度法检测牛奶及奶粉中的三聚氰胺. 化学分析计量, 2010, 19(1), 36-39.
[35] Liu, Baosheng; Xue, Chunli; Wang, Jing; Yang, Chao; Zhao, Fengli; Lv, Yunkai. Study on the competitive reaction between bovine serum albumin and neomycin with ponceau S as fluorescence probe. Journal of Luminescence, 2010, 130(11): 1999-2003. DOI: 10.1016/j.jlumin.2010.05.017.
[34] Yan, Hongyuan; Du, Jingjing; Zhang, Xiguo; Yang, Gengliang; Row, Kyung Ho; Lv, Yunkai. Ultrasound-assisted dispersive liquid-liquid microextraction coupled with capillary gas chromatography for simultaneous analysis of nine pyrethroids in domestic wastewaters. Journal of Separation Science, 2010, 33(12): 1829-1835. DOI: 10.1002/jssc.200900716.
[33] 吕运开,边超,王燕桓,秦新英. 固相萃取-离子对液相色谱法测定保健品中的叶酸. 食品科学,2009, 30(14), 171-174.
[32] 秦新英, 边, 超, 吕树芳, 吕运开, 王燕桓. RP-HPLC内标法测定双黄连注射液中黄芩苷的含量. 河北大学学报, 2009, 29(4), 394-397.
[31] 刘保生, 赵风利, 薛春丽, 王晶, 吕运开. 荧光光谱在研究氯霉素与沙拉沙星间拮抗作用中的应用. 物理化学学报, 2009, 25(9): 1861-1866.
[30] 陈玉海, 赵风利, 张彦青, 吕运开, 刘保生. 铕-环丙沙星的稀土敏化荧光研究及应用. 分析试验室, 2009, 28(5): 31-33.
[29] Li Bao-hui, Tian Bao-juan, Lv Yun-kai. Simultaneous Chiral Separation of Geometry Isomers and Enantiomers of Nateglinide by Capillary Electrophoresis with Mixture of CD Derivations as Chiral Selector. Analytical Letters, 2008, 41(17): 3177- 3186
[28] 吕运开*,边超,赵宁,王燕桓. 固相萃取-高效液相色谱法快速测定水中痕量苯并(a)芘. 中国给水排水, 2008, 24(16): 88-90
[27] 刘保生, 张彦青, 王云科, 吕运开. 胶束体系中荧光素与四溴荧光素间能量转移条件及模型研究. 光谱学与光谱分析, 2008, 7: 1600-1602.
[26] 刘保生, 王云科, 张彦青, 傅丽, 吕运开. 铽-环丙沙星与罗丹明B间稀土敏化荧光能量转移机理研究. 光谱学与光谱分析, 2008, 1: 153-155.
[25] Sun, Han-wen; He, Pan; Lv, Yun-kai; Liang, Shu-xuan, Effective separation and simultaneous determination of seven fluoroquinolones by capillary electrophoresis with diode-array detector, Journal Of Chromatography B-Analytical Technologies In The Biomedical And Life Sciences, 2007, 852, 1-2, 145, 151, , DOI, 10.1016/j.jchromb.2007.01.016
[24] 刘保生, 傅丽, 王云科, 曹冬林, 吕运开. 铜-洛美沙星-曙红三元络合物分光光度法测定洛美沙星. 分析试验室, 2007, 9: 31-33.
[23] 刘保生, 王云科, 张彦青, 吕运开. 铽-环丙沙星稀土敏化荧光猝灭法测定叶酸. 分析化学, 2007, 7:1067-1070.
[22] 李丽清, 孙汉文, 李伟娜, 陈雪艳, 吕运开. 高锰酸钾-甲醛-氨基喋呤化学发光体系的研究. 河北大学学报(自然科学版), 2007, 3: 270-274.
[21] 孙汉文, 陈雪艳, 李丽清, 吕运开. 流动注射-化学发光法测定药物与体液中的左氧氟沙星. 河北大学学报(自然科学版), 2006, 2: 161-165.
[20] 吕运开,严秀平. 分子印迹溶胶-凝胶材料的制备及应用. 分析化学, 2005, 33(2), 254-260.
[19] Lu Yun-kai, Yan Xiu-Ping. An Imprinted Organic-Inorganic Hybrid Sorbent for Selective Separation of Cadmium from Aqueous Solution. Analytical. Chemistry, 2004, 76(2), 453-457. DOI: 10.1021/ac0347718
[18] Lu Yun-kai, Sun Han-Wen, Yuan Chun-Gang, and Yan Xiu-Ping. Simultaneous Determination of Trace Cadmium and Arsenic in Biological Samples by Hydride Generation-Double Channel Atomic Fluorescence Spectrometry. Analytical Chemistry, 2002, 74(7): 1525-1529.
[17] 锁然, 吕运开, 孙汉文, 张德强, 碱式模式氢化物发生原子荧光法测定食用菌中痕量锗. 分析试验室, 2001, 20(1): 82-84
[16] 赵文革, 吕运开, 王春, 催化光度法测定粮食中的痕量锰. 分析试验室, 2001, 20(4): 73-75
[15] 孙汉文, 锁然, 张德强, 吕运开. 同时测定中草药中痕量铅和汞的氢化物原子荧光法. 分析测试学报, 2002, 3: 67-69.
[14] 吕运开, 孙汉文, 尿中痕量碲测定的萃取—氢化物发生原子荧光光谱法, 分析测试学报, 2000, 19(4): 24-27
[13] 吕运开, 孙汉文, 锁然,氢化物发生-原子荧光法测定苹果中富集的硒. 食品科学, 2000, 21(9): 43-45
[12] 锁然, 吕运开, 孙汉文, 张德强, 水中痕量铅的氢化物原子荧光测定, 河北大学学报(自然科学版), 2000, 20(4): 339-34
[11] 吕运开,吕运开, 马志广, 高俊刚, 加强实验队伍建设 提高实验室整体水平, 河北大学学报, 1999, 19: 53-54
[10] 吕运开,马勇, 高俊刚, 专业实验室改革的实践与探索, 河北大学学报, 1999, 19(s), 14-15
[9] 孙汉文,吕运开,张德强, 用氢化物原子荧光光谱法测定蔬菜中的痕量砷, 河北大学学报, 1999, 19(3), 246-251
[8] 马志广, 郄录江, 申世刚, 单金媛, 吕运开, 郭花枝, 赵建国. 物理化学实验数据处理程序的设计. 河北大学学报(自然科学版), 1999, (S1): 57-59.
[7] 吕运开,确保安全、加强试剂管理, 实验室科学, 1998, 2: 88-89.
[6] 吕运开,孙汉文, 氢化物发生-原子荧光光谱分析中的干扰机理, 河北大学学报, 1998, 18(s), 31-36
[5] 李记太, 李立军, 张能芳, 吕运开, DL-α-苯甘氨酸合成方法的改进, 1997, 5 (2) :000215-217
[4] 杜建军,吕运开. PVC热收缩薄膜吹塑生产工艺, 国外包装文摘, 1995, 33-8, 1
[3] 李慧章, 张能芳, 李记太, 吕运开, Landini苯甘氨酸合成方法的改进, 化学试剂, 1995 (2) :122-122.
[2] 李记太,周晓丽, 吕运开, 超声波作用下二苯甲酮的还原, 河北大学学报, 1994, 14(2), 67-71.
[1] 吕运开, 贾联臣, 四氢呋喃聚合反应中的光化学引发剂, 许昌师专学报, 1993, 12(3), 26-30